PUBLICATIONS

 

MITOCHONDRIA

GENETICS

CHOLESTEROL EFFLUX

Mitochondria General

Non-invasive evaluation of buccal respiratory chain enzyme dysfunction in mitochondrial disease: Comparison with studies in muscle biopsy  

Link: https://www.ncbi.nlm.nih.gov/pubmed/?term=Non-invasive+evaluation+of+buccal+respiratory+chain+enzyme+dysfunction+in+mitochondrial+disease%3A+Comparison+with+studies+in+muscle+biopsy

Evaluation and Treatment of Patients with Autism and Mitochondrial Disease

Link: http://epidemicanswers.org/wp-content/uploads/2010/05/Dr.-Richard-Kelly-Autism_Mitochondrial_Disease.pdf

Mitochondrial disorders: An overview of diagnostic tools and new diagnostic trends

Link: http://virtualmdpractice.com/documents/OverviewofDiagnosticToolsandnewtrendsWebsitever_000.PDF

Mitochondria in precision medicine; linking bioenergetics and metabolomics in platelets

Link: https://www.sciencedirect.com/science/article/pii/S2213231719302034

Chapter X. Phosphorylation of mammalian cytochrome c and cytochrome c oxidase in the regulation of cell destiny: respiration, apoptosis, and human disease

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727645/

Publications

We are continually updating our lists of publications.

Please click on the corresponding publications listed below for further information.

Mitochondria and Aging:

Reconsidering the Role of Mitochondria in Aging

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779179/

Mitochondria, Estrogen and Female Brain Aging

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934418/

Brain ageing and neurodegeneration: from a mitochondrial point of view

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724505/

Mitochondria and Autism:

Clinical and Molecular Characteristics of Mitochondrial Dysfunction in Autism Spectrum Disorder

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132446/

Mitochondrial Dysfunction in Autism

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915058/

Mitochondrial dysfunction in the gastrointestinal mucosa of children with autism: A blinded case-control study

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640251/

Evidence of Mitochondrial Dysfunction in Autism: Biochemical Links, Genetic-Based Associations, and Non-Energy-Related Mechanisms

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467355/

Gastrointestinal dysfunction in autism spectrum disorder: the role of the mitochondria and the enteric microbiome

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425813/

Evidence of reactive oxygen species-mediated damage to mitochondrial DNA in children with typical autism.

Link: https://www.ncbi.nlm.nih.gov/pubmed/23347615

Mitochondria and Cancer:

Mitochondrial Determinants of Cancer Health Disparities

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673596/

Mitochondria and Cancer

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779192/

Mitochondria and cancer- Doug Wallace

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371788/pdf/nihms-656316.pdf

Mitochondria and Cardiovascular Disease:

Ischemic Heart Disease:

Mitochondrial Oxidative Phosphorylation defect in the Heart of Subjects with

coronary Artery Disease

Link:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527853/pdf/41598_2019_Article_43761.pdf

 

Heart Failure:

Targeting mitochondrial dysfunction and oxidative stress in heart failure: challenges and opportunities

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309415/pdf/nihms-995385.pdf

Mitochondrial dysfunction in heart failure

Link:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855291/pdf/nihms406401.pdf

Mitochondria and Chronic Fatigue Syndrome

Chronic fatigue syndrome and mitochondrial dysfunction

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680051/pdf/ijcem0001-0001.pdf

Mitochondrial dysfunction and the pathophysiology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403556/pdf/ijcem0005-0208.pdf

Targeting mitochondrial dysfunction in the treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) – a clinical audit

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515971/pdf/ijcem0006-0001.pdf

Mitochondria and Down's Syndrome:

Mitochondrial dysfunction in down syndrome: molecular mechanisms and therapeutic targets

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016872/pdf/10020_2018_Article_4.pdf

Mitochondrial and Epilepsy:

Mitochondrial Involvement and Oxidative Stress in Temporal Lobe Epilepsy

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043127/pdf/nihms445387.pdf

Mitochondrial dysfunction and oxidative stress: a contributing link to acquired epilepsy?

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102435/pdf/nihms294170.pdf

Mitochondria and Fibromyalgia:

Mitochondrial Dysfunction in Skeletal Muscle of a Fibromyalgia Model: The Potential Benefits of Melatonin

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386947/

Mitochondria and Immune function:

Diverse Roles of Mitochondria in Immune Responses: Novel Insights Into Immuno-Metabolism

Link: https://www.frontiersin.org/articles/10.3389/fimmu.2018.01605/full

Mitochondria and Infection:

Viral Infections:

Mitochondrial Dynamics and Viral infections: a close nexus

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500740/pdf/nihms655545.pdf

Redox Biology of Respiratory Viral Infections

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115776/

 

Fungal Infections:

Mitochondria and Fungal Pathogenesis: Drug Tolerance, Virulence, and Potential for Antifungal Therapy

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209048/

Exploiting mitochondria as targets for the development of new antifungals

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354164/

Exploring and exploiting the connection between mitochondria and the virulence

of human pathogenic fungi

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955198/

Mitochondria and Infertility:

Female Infertility:

Oocyte mitochondrial function and reproduction

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590773/

Mitochondrial functionality in female reproduction.

https://www.ncbi.nlm.nih.gov/pubmed/28894044

The role of mitochondria in the female germline: Implications to fertility and inheritance of mitochondrial diseases

Link: https://onlinelibrary.wiley.com/doi/abs/10.1002/cbin.10947

Mitochondria as a tool for oocyte rejuvenation.

Link: https://www.ncbi.nlm.nih.gov/pubmed/30611551

 

Male Infertility:

Genetics of mitochondrial dysfunction and infertility.

Link: https://www.ncbi.nlm.nih.gov/pubmed/27748512

Mitochondria and Inflammation:

Mitochondrial Dysfunction and Damage Associated Molecular Patterns (DAMPs) in Chronic Inflammatory Diseases

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988941/

Mitochondrial Redox System, Dynamics, and Dysfunction in Lung Inflammaging and COPD

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154857/

Mitochondria and inflammation.

Link: https://www.ncbi.nlm.nih.gov/pubmed/29244932

Mitochondrial dysfunction as a trigger of innate immune responses and inflammation.

Link: https://www.ncbi.nlm.nih.gov/pubmed/28765055

Mitochondria and Liver Disease:

NAFLD:

Role of Mitochondria in Nonalcoholic Fatty Liver Disease

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057755/

Role of mitochondria in nonalcoholic fatty liver disease–from origin to propagation.

Link: https://www.ncbi.nlm.nih.gov/pubmed/22484459

Role of Oxidative Stress in Pathophysiology of Nonalcoholic Fatty Liver Disease.

Link: https://www.ncbi.nlm.nih.gov/pubmed/29991976

Mitochondria and Lyme’s Disease:

New insights into Lyme disease.

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392059/

Mitochondria and Neurodegeneration:

Alzheimers:

Dysfunctional Mitochondrial Bioenergetics and Synaptic Degeneration in Alzheimer Disease

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433209/

Mitochondrial Dysfunction: Different Routes to Alzheimers Disease Therapy

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158152/

Mitochondrial dysfunction and Alzheimer’s disease.

Link: https://www.ncbi.nlm.nih.gov/pubmed/20624441

Parkinson’s Disease:

Calcium, mitochondrial dysfunction and slowing the progression of Parkinson’s

disease.

Link:  https://www.ncbi.nlm.nih.gov/pubmed/28780195

Alpha-synuclein: Pathology, mitochondrial dysfunction and neuroinflammation in Parkinson’s disease.

Link: https://www.ncbi.nlm.nih.gov/pubmed/28400134

Mitoepigenetics and Neurodegenerative Diseases.

Link: https://www.ncbi.nlm.nih.gov/pubmed/30837953

Mitochondrial DNA and primary mitochondrial dysfunction in Parkinson’s disease.

Link: https://www.ncbi.nlm.nih.gov/pubmed/28251677

 

Parkinson’s Disease Treatment:

Antioxidants, supplements, and Parkinson’s disease.

Link: https://www.ncbi.nlm.nih.gov/pubmed/16622156

Oral N-acetyl-cysteine attenuates loss of dopaminergic terminals in alpha-synuclein overexpressing mice.

Link: https://www.ncbi.nlm.nih.gov/pubmed/20808797

Vitamin E therapy in Parkinson‘s disease.

Link: https://www.ncbi.nlm.nih.gov/pubmed/12821288

Neuroprotection of Coenzyme Q10 in Neurodegenerative Diseases

Link: https://www.ncbi.nlm.nih.gov/pubmed/26311425

Neuropsychiatric Disease:

Mitochondrial Involvement in Mental Disorders: Energy Metabolism and Genetic and Environmental Factors.

Link: https://www.ncbi.nlm.nih.gov/pubmed/30747417

Mitochondrial dysfunction and psychiatric disorders.

Link: https://www.ncbi.nlm.nih.gov/pubmed/18979198

 

Depression:

Mitochondrial Dysfunction in Depression.

Link: https://www.ncbi.nlm.nih.gov/pubmed/26923778

Mitochondria and Mood: Mitochondrial Dysfunction as a Key Player in the Manifestation of Depression. 

Link: https://www.ncbi.nlm.nih.gov/pubmed/29928190

 

Depression Treatment:

N-Acetylcysteine in depressive symptoms and functionality: a systematic review and meta-analysis.

Link: https://www.ncbi.nlm.nih.gov/pubmed/27137430

Antidepressant effects of open-label treatment with Coenzyme Q10 in Geriatric Bipolar Depression 

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414830/

Lower plasma Coenzyme Q10 in depression: a marker for treatment resistance and chronic fatigue in depression and a risk factor to cardiovascular disorder in that illness.

Link: https://www.ncbi.nlm.nih.gov/pubmed/20010493

Acetyl-L-Carnitine Supplementation and the Treatment of Depressive Symptoms: A Systematic Review and Meta-Analysis. 

Link: https://www.ncbi.nlm.nih.gov/pubmed/29076953

 

Schizophrenia

Mitochondrial dysfunction in schizophrenia: pathways, mechanisms and implications.

Link: https://www.ncbi.nlm.nih.gov/pubmed/25446950

An emerging role for mitochondrial dynamics in schizophrenia.

Link: https://www.ncbi.nlm.nih.gov/pubmed/28526279

 

Bipolar Disorder

Mitochondrial Dysfunctions in Bipolar Disorder: Effect of the Disease and Pharmacotherapy.

Link: https://www.ncbi.nlm.nih.gov/pubmed/27978794

 

Mitochondria and Stroke:

Healthy mitochondria for stroke cells

Link: https://www.ncbi.nlm.nih.gov/pubmed/30450414

Mitochondrial targeting as a novel therapy for stroke

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187947/

Mitochondria and Sarcopenia:

Mitochondria Initiate and Regulate Sarcopenia

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357179/

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