Mitochondrial medicine

Buccal Swab Test to analyze the Mitochondrial Electron Transport Chain Complex (ETC I & IV)

Who should consider MitoSwab Testing?

Patients with the following symptoms or conditions may consider the MitoSwab Test: Clinical Symptoms involving more than three organs systems, Developmental Delay, Loss of skills, Learning Disabilities, Autism Spectrum Disorder, Muscle Weakness, Seizures, Peripheral Neuropathy, Hearing Loss, Blindness, Ophthalmoplegia, Stroke Like Symptoms, Cerebral Palsy,

• Headache, Neuropsychiatric Symptoms, Cognitive dysfunction, Movement Difficulties, Heart Disease and Failure, Fatigue, Weakness, Liver or Kidney disease, Gastrointestinal Disorders, Severe constipation
• Diabetes, Increased risk of Infection, Thyroid and/or Adrenal Dysfunction, Autonomic Dysfunction, Neuropsychological changes characterized by confusion, disorientation, and memory loss.

Sample Collection Kit includes:

• Specimen: 4 Buccal Swab (Cheek Swabs)
• Collection tube/Swab: Buccal Swab

• Specimen Packaging: Clear plastic bag in the Uline envelope with frozen ice pack

• Three Ice Packs: Ice packs need to be frozen prior to collection of swab
• How To Collect Sample: click here for video instruction
• Specimen Requirement: Buccal Swabs placed in frozen ice packs placed in the given temperature-controlled U Line envelope
• Rejection Criteria: Ice packs not Frozen or the swabs not frozen, Inadequate sample in the buccal swab
• Time for Report: 2-3 weeks

Buccal Swab Test Mitochondrial Electron Transport Chain Function Complex I, II, III, IV

Sample Collection Kit includes:

• Specimen: 4 Buccal Swab (Cheek Swabs)
• Collection tube/Swab: Buccal Swab
• Specimen transport: Transport in the ULine envelope with ice packs
• Specimen Requirement: Buccal Swabs placed in frozen ice packs placed in the given temperature-controlled U Line envelope
• Rejection Criteria: Ice packs not Frozen or the swabs not frozen, Inadequate sample in the buccal swab
• Time for Report: 3-4 weeks

Mitochondrial DNA Sequencing

Who should consider MitoSeQ and MitoSeQ Plus? 

Symptoms involving more than three organ systems, Developmental Delay, Loss of skills, Learning Disabilities, Autism Spectrum Disorder, Muscle Weakness, Seizures, Peripheral Neuropathy, Hearing Loss, Blindness, Ophthalmoplegia, Stroke Like Symptoms, Cerebral Palsy, Headache.

The Mitochondria has its own DNA. Mitochondrial DNA contains 37 genes, all of which are essential for normal mitochondrial function. In humans, mitochondrial DNA spans about 16,500 DNA building blocks (base pairs), representing a small fraction of the total DNA in cells.

Sample Collection:

• Specimen: Saliva, blood or other tissue samples

• Specimen collection: Click here

• Specimen Requirement: 
• Rejection Criteria: The sample must contain adequate DNA
• Time to Report: 4-8 weeks